HitPredict

Interactor 1: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Interactor 2: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20020773
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 414 Hs			1 325
+	Hs
		903188 TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		162000 HNRDL_HUMAN (62-376): 5.62e-71: 231: 23.60		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		852006 ROA3_HUMAN (98-269): 2.33e-69: 225: 28.57		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		162112 HNRDL_HUMAN (62-376): 5.62e-71: 231: 23.60		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		852133 ROA3_HUMAN (98-269): 2.33e-69: 225: 28.57		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		903196 PABP4_HUMAN (98-274): 3.77e-37: 144: 19.02		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		852125 ROA3_HUMAN (98-269): 2.33e-69: 225: 28.57		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		516438 PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Sc
		376807 PABP_YEAST (86-269): 2.74e-34: 136: 21.88		EIF3I_YEAST (141-325): 9.4e-30: 117: 13.36
+	Hs
		903216 HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		1048176 HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		1048172 HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05