Interactor 1: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Interactor 2: SF3B3 (Q15393)
Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (STAF130) (Spliceosome-associated protein 130) (SAP 130)
Gene: SF3B3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 32814053
Identification Methods two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CPSF_A~RRM_1
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008380 - RNA splicing
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 414
Hs

1 1217
+ Sc
+ Hs
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024