HitPredict

Interactor 1: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Interactor 2: DHX57 (Q6P158)
Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57)
Gene: DHX57

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20020773
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 414 Hs			1 1386
+	Hs
		994140 TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00		DHX9_HUMAN (269-1383): 0: 894: 29.56
+	Hs
		1025960 TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00		DHX36_HUMAN (395-1386): 0: 863: 37.98
+	Hs
		162022 HNRDL_HUMAN (62-376): 5.62e-71: 231: 23.60		DHX9_HUMAN (269-1383): 0: 894: 29.56
+	Hs
		852024 ROA3_HUMAN (98-269): 2.33e-69: 225: 28.57		DHX9_HUMAN (269-1383): 0: 894: 29.56
+	Bt
		898864 PABP1_BOVIN (2-382): 7.78e-31: 126: 15.95		DHX9_BOVIN (270-1383): 0: 886: 29.76
+	Hs
		994161 HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93		DHX9_HUMAN (269-1383): 0: 894: 29.56
+	Hs
		1025812 TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00		DHX30_HUMAN (473-1361): 0: 709: 30.91
+	Hs
		162079 HNRDL_HUMAN (62-376): 5.62e-71: 231: 23.60		DHX30_HUMAN (473-1361): 0: 709: 30.91
+	Sc
		376861 PABP_YEAST (86-269): 2.74e-34: 136: 21.88		PRP43_YEAST (452-1338): 0: 757: 25.11
+	Zm
		9780 A0A1D6EZQ5_MAIZE (2-411): 2.75e-27: 115: 14.93		A0A1D6GAN5_MAIZE (322-1366): 0: 716: 28.13
+	Sc
		376941 PABP_YEAST (86-269): 2.74e-34: 136: 21.88		YL419_YEAST (473-1386): 0: 685: 26.16
+	Sc
		376924 PABP_YEAST (86-269): 2.74e-34: 136: 21.88		DHR1_YEAST (417-1320): 0: 681: 22.58
+	Hs
		1048117 HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93		DHX30_HUMAN (473-1361): 0: 709: 30.91
+	Hs
		1025964 TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00		YTDC2_HUMAN (513-741): 5.46e-59: 226: 51.87