Interactor 1: NDP (Q00604)
Norrin (Norrie disease protein) (X-linked exudative vitreoretinopathy 2 protein)
Gene: NDP
Interactor 2: SIR1 (Q96EB6)
NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]
Gene: SIRT1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.55 | 0.458 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 40425833 |
| Identification Methods | proximity labelling technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001525 - angiogenesis GO:0007179 - transforming growth factor beta receptor signaling pathway GO:0016567 - protein ubiquitination GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction and 1 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
