HitPredict

Interactor 1: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 414 Hs			1 779
+	Hs
		162154 HNRDL_HUMAN (62-376): 5.62e-71: 231: 23.60		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		852171 ROA3_HUMAN (98-269): 2.33e-69: 225: 28.57		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1119145 PAP1L_HUMAN (96-274): 7.74e-38: 146: 17.74		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1031462 PABP4_HUMAN (98-274): 3.77e-37: 144: 19.02		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1329982 PABP3_HUMAN (2-382): 7.84e-31: 126: 16.41		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		516692 PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1048228 HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1025792 TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		162072 HNRDL_HUMAN (62-376): 5.62e-71: 231: 23.60		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		852085 ROA3_HUMAN (98-269): 2.33e-69: 225: 28.57		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Sc
		376773 PABP_YEAST (86-269): 2.74e-34: 136: 21.88		OSH3_YEAST (21-718): 7.21e-65: 235: 11.98
+	Hs
		1035403 PABP3_HUMAN (2-382): 7.84e-31: 126: 16.41		GAB1_HUMAN (52-611): 6.48e-53: 197: 13.92
+	Hs
		516497 PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95		GAB1_HUMAN (52-611): 6.48e-53: 197: 13.92
+	Hs
		516557 PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1048106 HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1153330 MSI2H_HUMAN (41-207): 5.16e-20: 92.2: 23.81		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1233367 PABP3_HUMAN (2-382): 7.84e-31: 126: 16.41		SESQ1_HUMAN (40-169): 5.2e-35: 135: 28.03
+	Hs
		1048286 HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93		PKHA6_HUMAN (3-364): 2.39e-40: 162: 26.02
+	Hs
		1231338 PABP3_HUMAN (2-382): 7.84e-31: 126: 16.41		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		516588 PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93