HitPredict

Interactor 1: ROA0 (Q13151)
Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0)
Gene: HNRNPA0

Interactor 2: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	26318153, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0035925 - mRNA 3'-UTR AU-rich region binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 305 Hs			1 355
+	Hs
		609857 ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		161962 ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42		HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63
+	Hs
		610017 ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42		ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89
+	Hs
		609770 ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42		ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02
+	Hs
		516358 ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		609713 ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		852037 ROA0_HUMAN (1-268): 2.87e-55: 183: 100.00		ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02
+	Hs
		162035 PABP4_HUMAN (5-185): 2.85e-44: 161: 19.67		HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63
+	Hs
		453146 ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		609837 ROA0_HUMAN (1-268): 2.87e-55: 183: 100.00		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		609894 ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42		RA1L2_HUMAN (46-167): 1.11e-13: 72.9: 27.87
+	Hs
		201642 MSI1H_HUMAN (3-304): 4.84e-61: 199: 29.56		MSI1H_HUMAN (21-180): 2.38e-16: 81: 28.13
+	Mm
		1142607 MSI1H_MOUSE (3-304): 1.09e-60: 199: 29.87		MSI1H_MOUSE (21-180): 7.88e-16: 79.4: 28.13
+	Hs
		201699 MSI1H_HUMAN (3-304): 4.84e-61: 199: 29.56		MSI2H_HUMAN (21-198): 1.49e-15: 78.3: 26.82
+	Hs
		453324 ROA0_HUMAN (1-268): 2.87e-55: 183: 100.00		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		1288208 MSI2H_HUMAN (5-303): 2.55e-56: 186: 32.11		MSI2H_HUMAN (21-198): 1.49e-15: 78.3: 26.82
+	Hs
		1026066 ROA0_HUMAN (1-268): 2.87e-55: 183: 100.00		RA1L2_HUMAN (46-167): 1.11e-13: 72.9: 27.87
+	Hs
		453331 PABP4_HUMAN (5-185): 2.85e-44: 161: 19.67		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		474021 PABP4_HUMAN (5-185): 2.85e-44: 161: 19.67		PAB4L_HUMAN (179-259): 1.74e-16: 81.7: 18.29