HitPredict

Interactor 1: PAK1 (Q13153)
Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)
Gene: PAK1

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~fn3
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 545 Hs			1 783
+	Hs
		1026923 PAK2_HUMAN (1-544): 2.14e-168: 489: 74.82		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		682189 AKT2_HUMAN (141-544): 1.54e-138: 411: 22.52		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		681909 AKT1_HUMAN (145-544): 8.19e-134: 399: 21.71		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		568710 KAPCA_HUMAN (228-544): 8.55e-131: 386: 23.62		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		610741 KAPCB_HUMAN (228-544): 1.13e-129: 383: 23.31		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1023065 STK4_HUMAN (247-545): 2.66e-127: 382: 41.20		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1027387 STK3_HUMAN (245-545): 7.24e-127: 381: 41.25		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172483 STK24_HUMAN (264-541): 1.36e-121: 366: 43.93		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1026219 PAK1_HUMAN (1-545): 0: 558: 100.00		FSD1_HUMAN (345-775): 1.45e-80: 268: 21.72
+	Hs
		1026943 PAK2_HUMAN (1-544): 2.14e-168: 489: 74.82		FSD1_HUMAN (345-775): 1.45e-80: 268: 21.72
+	Hs
		331033 PAK4_HUMAN (68-270): 7.44e-14: 76.1: 18.36		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		568758 KAPCA_HUMAN (228-544): 8.55e-131: 386: 23.62		TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40
+	Hs
		568786 KAPCA_HUMAN (228-544): 8.55e-131: 386: 23.62		TRI55_HUMAN (189-505): 9.32e-81: 270: 19.57
+	Hs
		536810 PAK1_HUMAN (1-545): 0: 558: 100.00		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		537109 STK26_HUMAN (262-545): 3.56e-122: 367: 43.71		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		331090 PAK4_HUMAN (68-270): 7.44e-14: 76.1: 18.36		TRI36_HUMAN (115-771): 5.52e-100: 327: 20.16
+	Hs
		131546 STK25_HUMAN (265-545): 2.72e-67: 225: 44.17		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		331009 PAK4_HUMAN (68-270): 7.44e-14: 76.1: 18.36		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29