Interactor 1: FADD (Q13158)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Growth-inhibiting gene 3 protein) (Mediator of receptor induced toxicity)
Gene: FADD

Interactor 2: FADD (Q13158)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Growth-inhibiting gene 3 protein) (Mediator of receptor induced toxicity)
Gene: FADD

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 27321185, 30561431, 32296183, 16762833, 16410793, 25502805, 31515488, unassigned1304, 7536190, 8681376
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, fluorescent resonance energy transfer, virotrap, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Death~Death, DED~DED
Common GO terms GO:0001822 - kidney development
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002020 - protease binding
GO:0002821 - positive regulation of adaptive immune response
GO:0005123 - death receptor binding
and 51 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 208
Hs

1 208
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Last updated: 15 Jul 2024