Interactor 1: FADD (Q13158)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Growth-inhibiting gene 3 protein) (Mediator of receptor induced toxicity)
Gene: FADD
Interactor 2: FADD (Q13158)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Growth-inhibiting gene 3 protein) (Mediator of receptor induced toxicity)
Gene: FADD
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.94 | 1.00 | 0.970 |
The method score is based on:
Property | Details |
---|---|
Experiments | 27321185, 30561431, 32296183, 16762833, 16410793, 25502805, 31515488, unassigned1304, 7536190, 8681376 |
Identification Methods | affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, fluorescent resonance energy transfer, virotrap, two hybrid array, two hybrid prey pooling approach, validated two hybrid |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Death~Death, DED~DED |
Common GO terms | GO:0001822 - kidney development GO:0001916 - positive regulation of T cell mediated cytotoxicity GO:0002020 - protease binding GO:0002821 - positive regulation of adaptive immune response GO:0005123 - death receptor binding and 51 others more... |
Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024