Interactor 1: FADD (Q13158)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Growth-inhibiting gene 3 protein) (Mediator of receptor induced toxicity)
Gene: FADD
Interactor 2: TRADD (Q15628)
Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain)
Gene: TRADD
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.980 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30561431, 32296183, 8565075, 21724995, 12911633, 16919273, 12107169, 12796506, 24686082, 23955153, 11464215, 21183682, 11112409, unassigned1304 |
| Identification Methods | affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, experimental interaction detection, virotrap, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Death~Death |
| Common GO terms | GO:0005164 - tumor necrosis factor receptor binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006915 - apoptotic process and 8 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
