HitPredict

Interactor 1: FADD (Q13158)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Growth-inhibiting gene 3 protein) (Mediator of receptor induced toxicity)
Gene: FADD

Interactor 2: RIPK3 (Q9Y572)
Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3)
Gene: RIPK3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.949

The method score is based on:

Property Details
Experiments 26786097, 30420664, 37085671, 22864571, 27560715, 21052097, 19524513
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DED~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0033077 - T cell differentiation in thymus
GO:0043029 - T cell homeostasis
GO:0044877 - protein-containing complex binding
and 6 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 208
Hs

1 518
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024