Interactor 1: PAK2 (Q13177)
Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]
Gene: PAK2

Interactor 2: PAK2 (Q13177)
Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]
Gene: PAK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.931

The method score is based on:

Property Details
Experiments 7673144, 15908432, 12453877, 16837009, 21555521
Identification Methods enzymatic study, protein kinase assay, light scattering, cosedimentation in solution
Interaction Type direct interaction, phosphorylation reaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PBD~PBD, PBD~Pkinase, Pkinase~Pkinase
Common GO terms GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0003300 - cardiac muscle hypertrophy
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
and 38 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 524
Hs

1 524
+ Rn
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Ce
+ Hs
+ Hs
+ At
+ At
+ At
+ At
+ Ce
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024