HitPredict

Interactor 1: PAK2 (Q13177)
Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]
Gene: PAK2

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~fn3
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 524 Hs			1 783
+	Hs
		1026180 PAK1_HUMAN (1-523): 6.81e-169: 490: 74.63		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		682189 AKT2_HUMAN (141-523): 2.01e-138: 410: 22.79		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		681909 AKT1_HUMAN (141-523): 1.99e-133: 397: 21.83		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		568710 KAPCA_HUMAN (207-520): 9.62e-131: 385: 22.91		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		610741 KAPCB_HUMAN (207-524): 1.39e-130: 385: 22.94		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1027387 STK3_HUMAN (224-524): 1.89e-125: 377: 41.25		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1023065 STK4_HUMAN (221-518): 9.32e-125: 375: 40.00		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172483 STK24_HUMAN (243-513): 1.32e-65: 221: 45.06		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1026943 PAK2_HUMAN (1-524): 0: 538: 100.00		FSD1_HUMAN (345-775): 1.45e-80: 268: 21.72
+	Hs
		1026219 PAK1_HUMAN (1-523): 6.81e-169: 490: 74.63		FSD1_HUMAN (345-775): 1.45e-80: 268: 21.72
+	Hs
		331033 PAK4_HUMAN (67-236): 2.65e-10: 64.9: 21.55		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		568758 KAPCA_HUMAN (207-520): 9.62e-131: 385: 22.91		TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40
+	Hs
		568786 KAPCA_HUMAN (207-520): 9.62e-131: 385: 22.91		TRI55_HUMAN (189-505): 9.32e-81: 270: 19.57
+	Hs
		536810 PAK1_HUMAN (1-523): 6.81e-169: 490: 74.63		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		331090 PAK4_HUMAN (67-236): 2.65e-10: 64.9: 21.55		TRI36_HUMAN (115-771): 5.52e-100: 327: 20.16
+	Hs
		537109 STK26_HUMAN (241-513): 3.68e-66: 221: 45.09		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		131546 STK25_HUMAN (244-513): 7.96e-64: 215: 44.12		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		331009 PAK4_HUMAN (67-236): 2.65e-10: 64.9: 21.55		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29