HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: LRIF1 (Q5T3J3)
Ligand-dependent nuclear receptor-interacting factor 1 (HP1-binding protein enriched in inactive X chromosome protein 1) (HBiX1) (Receptor-interacting factor 1)
Gene: LRIF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.749

Property	Details
Experiments	32296183, 24981860, 27705803, 34079125, 33961781, unassigned1304, 23542155, 21888893
Identification Methods	two hybrid, affinity chromatography technology, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 769
+	Hs
		800411 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		LRIF1_HUMAN (1-769): 0: 1293: 100.00
+	Hs
		949805 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		LRIF1_HUMAN (1-769): 0: 1293: 100.00
+	Hs
		1133125 SUV92_HUMAN (6-156): 4.05e-43: 149: 25.15		LRIF1_HUMAN (1-769): 0: 1293: 100.00
+	Mm
		1208144 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		LRIF1_MOUSE (1-769): 0: 1189: 68.60
+	Mm
		1143036 CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89		LRIF1_MOUSE (1-769): 0: 1189: 68.60
+	Mm
		949954 CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33		LRIF1_MOUSE (1-769): 0: 1189: 68.60