HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: Z280D (Q6N043)
Zinc finger protein 280D (Suppressor of hairy wing homolog 4) (Zinc finger protein 634)
Gene: ZNF280D

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.717

Property	Details
Experiments	27705803, 32296183, 34079125, 21888893, unassigned1304
Identification Methods	affinity chromatography technology, two hybrid, proximity labelling technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 979
+	Hs
		64140 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN729_HUMAN (29-831): 0: 699: 12.80
+	Hs
		1027135 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		Z280C_HUMAN (3-734): 3.44e-174: 527: 67.39
+	Hs
		1027143 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN420_HUMAN (367-911): 9.98e-164: 498: 13.71
+	Hs
		67424 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN850_HUMAN (31-500): 1.26e-145: 463: 13.92
+	Hs
		1027086 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		POGZ_HUMAN (26-831): 6.14e-141: 458: 31.97
+	Hs
		728565 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF93_HUMAN (470-911): 3.11e-106: 345: 11.46
+	Hs
		1027217 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN184_HUMAN (529-964): 1.81e-80: 279: 9.54
+	Hs
		1027274 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN287_HUMAN (696-902): 8.36e-47: 182: 9.72
+	Hs
		1027188 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN479_HUMAN (222-508): 9.19e-39: 154: 20.69
+	Hs
		549158 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN250_HUMAN (222-506): 9.83e-38: 151: 20.71
+	Hs
		1027027 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN568_HUMAN (34-185): 1.81e-31: 133: 11.18
+	Hs
		1027126 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN615_HUMAN (736-911): 6.02e-23: 107: 10.27
+	Hs
		1027294 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN226_HUMAN (35-177): 7.04e-23: 106: 11.89
+	Hs
		983755 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF91_HUMAN (29-152): 1.13e-19: 97.4: 11.29
+	Hs
		1027211 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN607_HUMAN (737-910): 1.88e-19: 95.8: 7.50
+	Hs
		1027000 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN846_HUMAN (311-441): 6.07e-19: 93.5: 23.88
+	Hs
		1027345 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN337_HUMAN (32-167): 3.53e-11: 69.4: 12.41
+	Hs
		1027024 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN829_HUMAN (313-412): 1e-10: 66.9: 20.49
+	Hs
		258850 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		Z780A_HUMAN (714-879): 3.18e-10: 66: 8.14
+	Hs
		1027081 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN534_HUMAN (729-885): 2.34e-09: 63.3: 6.14