HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: Z280C (Q8ND82)
Zinc finger protein 280C (Suppressor of hairy wing homolog 3) (Zinc finger protein 633)
Gene: ZNF280C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.717

Property	Details
Experiments	27705803, 34079125, 32296183, 33961781, unassigned1304
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation, validated two hybrid, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 737
+	Hs
		1027056 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		Z280D_HUMAN (3-732): 0: 563: 66.98
+	Hs
		64140 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN729_HUMAN (70-721): 5.73e-179: 546: 11.83
+	Hs
		1027217 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN184_HUMAN (350-737): 3.63e-161: 485: 14.52
+	Hs
		67424 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN850_HUMAN (69-615): 5.61e-155: 479: 11.64
+	Hs
		988824 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN33A_HUMAN (70-647): 1.12e-157: 478: 11.55
+	Hs
		728565 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF93_HUMAN (339-737): 3.97e-142: 432: 15.44
+	Hs
		1027294 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN226_HUMAN (65-546): 2.44e-132: 412: 11.85
+	Hs
		1027086 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		POGZ_HUMAN (58-720): 3.2e-112: 372: 33.51
+	Hs
		1027126 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN615_HUMAN (453-737): 3.61e-85: 286: 9.12
+	Hs
		1027345 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN337_HUMAN (442-737): 1.33e-81: 277: 10.06
+	Hs
		983755 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF91_HUMAN (70-408): 9.65e-65: 235: 10.41
+	Hs
		1027143 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN420_HUMAN (535-737): 1.21e-52: 195: 10.22
+	Hs
		1027027 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN568_HUMAN (545-734): 9.32e-39: 154: 12.15
+	Hs
		1027201 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN570_HUMAN (440-730): 1.12e-37: 150: 13.20
+	Hs
		1027296 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		RBAK_HUMAN (72-300): 2.44e-31: 132: 9.58
+	Hs
		1027102 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN227_HUMAN (60-314): 9.17e-31: 131: 6.76
+	Hs
		1027189 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN333_HUMAN (236-471): 1.06e-23: 108: 17.37
+	Hs
		1027274 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN287_HUMAN (193-345): 5.76e-23: 106: 11.23
+	Hs
		62491 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN316_HUMAN (239-433): 1.42e-15: 83.1: 17.44
+	Hs
		1027150 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN480_HUMAN (531-730): 3.52e-15: 81.1: 12.45