HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: ZN274 (Q96GC6)
Neurotrophin receptor-interacting factor homolog (Zinc finger protein 274) (Zinc finger protein HFB101) (Zinc finger protein with KRAB and SCAN domains 19) (Zinc finger protein zfp2) (Zf2)
Gene: ZNF274

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	31403225
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 653
+	Hs
		728565 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF93_HUMAN (198-652): 3.52e-175: 514: 23.52
+	Hs
		67424 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN850_HUMAN (55-613): 1.39e-165: 504: 15.82
+	Hs
		64140 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN729_HUMAN (55-600): 8.73e-152: 472: 15.27
+	Hs
		258850 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		Z780A_HUMAN (332-652): 5.49e-127: 391: 27.10
+	Hs
		1027147 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN483_HUMAN (359-652): 3.17e-99: 321: 29.81
+	Hs
		1027126 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN615_HUMAN (55-418): 4.76e-71: 246: 4.55
+	Hs
		850777 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN75D_HUMAN (127-643): 1.01e-62: 218: 31.00
+	Hs
		1027081 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN534_HUMAN (64-338): 4.74e-49: 183: 5.80
+	Hs
		1027143 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN420_HUMAN (54-296): 2.05e-33: 138: 6.43
+	Hs
		161822 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN263_HUMAN (322-531): 1.2e-32: 135: 18.86
+	Hs
		1027167 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZKSC4_HUMAN (587-652): 4.27e-23: 105: 46.97
+	Hs
		1027150 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN480_HUMAN (2-79): 6.85e-23: 104: 39.74
+	Hs
		599068 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF10_HUMAN (1-86): 1.16e-18: 92: 55.81
+	Hs
		970657 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF45_HUMAN (54-263): 5e-18: 90.4: 9.55
+	Hs
		1027128 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN565_HUMAN (320-503): 8.37e-18: 88.9: 14.60
+	Hs
		983755 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF91_HUMAN (55-246): 4.94e-16: 84.2: 7.92
+	Hs
		565115 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF8_HUMAN (6-104): 9.28e-16: 82.8: 47.06
+	Hs
		1027027 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN568_HUMAN (55-224): 1.57e-11: 69.6: 5.59
+	Hs
		1027024 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN829_HUMAN (1-77): 1.33e-11: 68.9: 50.65
+	Hs
		240839 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		Z354A_HUMAN (552-653): 7.55e-09: 60.9: 25.49