HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: SENP7 (Q9BQF6)
Sentrin-specific protease 7 (EC 3.4.22.-) (SUMO-1-specific protease 2) (Sentrin/SUMO-specific protease SENP7)
Gene: SENP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	27705803, 34079125, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 1050
+	Hs
		800505 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		SENP7_HUMAN (1-1050): 0: 1109: 100.00
+	Mm
		613032 CBX3_MOUSE (1-183): 4.67e-71: 214: 99.45		SENP7_MOUSE (1-1049): 0: 1068: 69.65
+	Mm
		1143031 CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89		SENP7_MOUSE (1-1049): 0: 1068: 69.65
+	Mm
		949950 CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33		SENP7_MOUSE (1-1049): 0: 1068: 69.65
+	Hs
		1027246 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SENP6_HUMAN (911-1046): 1.23e-35: 149: 53.68
+	Hs
		316153 CBX6_HUMAN (21-124): 3.3e-27: 107: 27.78		SENP3_HUMAN (629-965): 5.55e-74: 257: 12.47
+	Hs
		316126 CBX6_HUMAN (21-124): 3.3e-27: 107: 27.78		SENP5_HUMAN (591-965): 1.31e-55: 209: 11.72