HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: BAZ1B (Q9UIG0)
Tyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor) (Williams-Beuren syndrome chromosomal region 10 protein) (Williams-Beuren syndrome chromosomal region 9 protein) (hWALp2)
Gene: BAZ1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Chromo~PHD
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005721 - pericentric heterochromatin GO:0006338 - chromatin remodeling GO:0006974 - DNA damage response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 1483
+	Hs
		1027317 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		BAZ2A_HUMAN (928-1448): 2.16e-77: 286: 19.06
+	Hs
		1027213 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		RSF1_HUMAN (477-1311): 3.83e-39: 161: 12.77
+	Hs
		998641 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		EP300_HUMAN (1229-1460): 7.94e-39: 161: 16.53
+	Hs
		631418 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		BRD2_HUMAN (1309-1450): 6.63e-28: 124: 21.53
+	Hs
		800357 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		EP300_HUMAN (1229-1460): 7.94e-39: 161: 16.53
+	Hs
		244377 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		BRD4_HUMAN (1308-1470): 1.84e-22: 107: 21.82
+	Hs
		1027010 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		BRD3_HUMAN (1331-1447): 6.43e-21: 101: 22.69
+	Hs
		631371 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		BRD2_HUMAN (1309-1450): 6.63e-28: 124: 21.53
+	Hs
		1027331 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		TRI33_HUMAN (1095-1321): 9.51e-15: 82.2: 16.74
+	Mm
		1145016 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		TIF1A_MOUSE (1094-1271): 1.02e-11: 72.2: 15.73
+	Hs
		170353 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		TIF1A_HUMAN (1094-1271): 1.56e-11: 71.4: 15.17
+	Mm
		1266178 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		TRI66_MOUSE (1157-1367): 1.1e-10: 69: 17.81
+	Hs
		782338 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		KDM5C_HUMAN (1183-1260): 1.24e-10: 68.6: 38.82
+	Hs
		244073 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		BRD4_HUMAN (1308-1470): 1.84e-22: 107: 21.82
+	Hs
		1027151 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		PHIP_HUMAN (1338-1418): 2.9e-09: 64.3: 40.00
+	Hs
		800386 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		BRD3_HUMAN (1331-1447): 6.43e-21: 101: 22.69
+	Mm
		1143020 CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89		TIF1A_MOUSE (1094-1271): 1.02e-11: 72.2: 15.73
+	Hs
		170295 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		TIF1A_HUMAN (1094-1271): 1.56e-11: 71.4: 15.17
+	Mm
		1143042 CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89		TRI66_MOUSE (1157-1367): 1.1e-10: 69: 17.81
+	Hs
		170331 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		TIF1A_HUMAN (1094-1271): 1.56e-11: 71.4: 15.17