HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: ARIP4 (Q9Y4B4)
Helicase ARIP4 (EC 3.6.4.12) (Androgen receptor-interacting protein 4) (RAD54-like protein 2)
Gene: RAD54L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Chromo~SNF2-rel_dom
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 1467
+	Hs
		1027145 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD5_HUMAN (68-1312): 0: 664: 15.55
+	Hs
		802429 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ATRX_HUMAN (23-1102): 0: 618: 28.83
+	Hs
		1027300 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD7_HUMAN (4-1356): 3.77e-177: 590: 14.82
+	Hs
		1027026 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD9_HUMAN (14-1126): 9.74e-177: 588: 15.90
+	Hs
		1027277 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD8_HUMAN (5-1340): 1.18e-174: 581: 15.27
+	Mm
		1161080 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		CHD4_MOUSE (135-1174): 1.2e-177: 581: 17.93
+	Hs
		1027001 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD4_HUMAN (68-1302): 2.04e-177: 580: 13.79
+	Hs
		846954 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SMCA4_HUMAN (23-1125): 2.79e-179: 580: 17.04
+	Hs
		800312 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		ATRX_HUMAN (23-1102): 0: 618: 28.83
+	Hs
		1018451 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD3_HUMAN (108-1366): 5.26e-175: 575: 14.30
+	Hs
		229384 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SMCA5_HUMAN (155-1097): 0: 573: 19.07
+	Hs
		658667 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SMCA1_HUMAN (169-1098): 0: 572: 18.62
+	Hs
		1027286 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		HELLS_HUMAN (116-938): 3.83e-177: 552: 20.95
+	Hs
		1027257 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SMRCD_HUMAN (19-911): 2.76e-174: 550: 19.04
+	Hs
		800320 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		SMCA4_HUMAN (23-1125): 2.79e-179: 580: 17.04
+	Hs
		800380 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		CHD4_HUMAN (68-1302): 2.04e-177: 580: 13.79
+	Hs
		800360 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		CHD3_HUMAN (108-1366): 5.26e-175: 575: 14.30
+	Hs
		800319 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		SMCA2_HUMAN (23-1109): 4.73e-176: 570: 16.85
+	Hs
		658650 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		SMCA1_HUMAN (169-1098): 0: 572: 18.62
+	Hs
		163601 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		BTAF1_HUMAN (420-896): 7.41e-35: 148: 26.83