HitPredict

Interactor 1: STK3 (Q13188)
Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]
Gene: STK3

Interactor 2: MLP3C (Q9BXW4)
Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma)
Gene: MAP1LC3C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.636

Property	Details
Experiments	31857374, 20562859
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 491 Hs			1 147
+	Hs
		306153 STK3_HUMAN (1-491): 1.83e-172: 496: 100.00		GBRAP_HUMAN (13-127): 3.44e-54: 168: 38.26
+	Hs
		891124 STK3_HUMAN (1-491): 1.83e-172: 496: 100.00		GBRL2_HUMAN (13-126): 1.65e-54: 168: 42.98
+	Hs
		1027430 STK3_HUMAN (1-491): 1.83e-172: 496: 100.00		MLP3A_HUMAN (7-126): 2.49e-53: 165: 59.17
+	Hs
		1027423 STK3_HUMAN (1-491): 1.83e-172: 496: 100.00		MLP3B_HUMAN (7-127): 8.15e-53: 164: 54.55
+	Hs
		1027427 STK3_HUMAN (1-491): 1.83e-172: 496: 100.00		GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47
+	Hs
		1023104 STK4_HUMAN (6-491): 3.63e-151: 441: 75.57		MLP3C_HUMAN (1-147): 4.64e-72: 214: 100.00
+	Hs
		306146 STK4_HUMAN (6-491): 3.63e-151: 441: 75.57		GBRAP_HUMAN (13-127): 3.44e-54: 168: 38.26
+	Hs
		891118 STK4_HUMAN (6-491): 3.63e-151: 441: 75.57		GBRL2_HUMAN (13-126): 1.65e-54: 168: 42.98
+	Hs
		1023110 STK4_HUMAN (6-491): 3.63e-151: 441: 75.57		MLP3A_HUMAN (7-126): 2.49e-53: 165: 59.17
+	Hs
		1023105 STK4_HUMAN (6-491): 3.63e-151: 441: 75.57		MLP3B_HUMAN (7-127): 8.15e-53: 164: 54.55
+	Hs
		1023108 STK4_HUMAN (6-491): 3.63e-151: 441: 75.57		GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47
+	Hs
		306141 M4K2_HUMAN (14-310): 3.14e-73: 249: 42.11		GBRAP_HUMAN (13-127): 3.44e-54: 168: 38.26
+	Hs
		891114 M4K2_HUMAN (14-310): 3.14e-73: 249: 42.11		GBRL2_HUMAN (13-126): 1.65e-54: 168: 42.98
+	Hs
		1018189 M4K2_HUMAN (14-310): 3.14e-73: 249: 42.11		GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47