HitPredict

Interactor 1: STK3 (Q13188)
Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]
Gene: STK3

Interactor 2: SAV1 (Q9H4B6)
Protein salvador homolog 1 (45 kDa WW domain protein) (hWW45)
Gene: SAV1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.766

The method score is based on:

Property Details
Experiments 26186194, 24366813, 28514442, 24981860, 33961781, 17379520, 21988832, 24255178, 32296183, 33162394, 32707033, 36736316, 20562859, 15688006, 23455922, 16930133, unassigned1304, 20920251
Identification Methods affinity chromatography technology, two hybrid, proximity labelling technology, anti tag coimmunoprecipitation, protein kinase assay, two hybrid array, two hybrid prey pooling approach, validated two hybrid, tandem affinity purification, pull down
Interaction Type physical association, direct interaction, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0035329 - hippo signaling
GO:0043065 - positive regulation of apoptotic process
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024