HitPredict

Interactor 1: CBLB (Q13191)
E3 ubiquitin-protein ligase CBL-B (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56) (RING-type E3 ubiquitin transferase CBL-B) (SH3-binding protein CBL-B) (Signal transduction protein CBL-B)
Gene: CBLB

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.763

The method score is based on:

Property Details
Experiments 23663663, 12177062, 12218189, 19531213, 17020880, 16228008, 32296183, 12874286, unassigned1304, 18680311, 19268472, 12829691
Identification Methods x-ray crystallography, pull down, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, isothermal titration calorimetry, two hybrid prey pooling approach, two hybrid array, competition binding, anti bait coimmunoprecipitation and 4 others

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Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0017124 - SH3 domain binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 15 Jul 2024