Interactor 1: PSMD2 (Q13200)
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
Gene: PSMD2

Interactor 2: Q53XL8 (Q53XL8)
Proteasome (Prosome, macropain) 26S subunit, ATPase, 1 (Proteasome 26S ATPase subunit 1) (cDNA, FLJ93843, Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 1(PSMC1), mRNA)
Gene: PSMC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 25416956
Identification Methods two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_lid_3~RPN1_C, AAA_lid_3~RPN1_RPN2_N
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0008540 - proteasome regulatory particle, base subcomplex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 908
Hs

1 440
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Last updated: 15 Jul 2024