HitPredict

Interactor 1: PSMD2 (Q13200)
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
Gene: PSMD2

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29509190, 25604459
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 908 Hs			1 530
+	Hs
		369522 PSMD2_HUMAN (1-908): 0: 1290: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		487393 PSMD2_HUMAN (1-908): 0: 1290: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		1269435 PSMD1_HUMAN (59-845): 0: 790: 17.31		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		370270 PSMD1_HUMAN (59-845): 0: 790: 17.31		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		487705 PSMD1_HUMAN (59-845): 0: 790: 17.31		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59