HitPredict

Interactor 1: PSMD2 (Q13200)
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
Gene: PSMD2

Interactor 2: HDAC6 (Q9UBN7)
Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35676659, 25036637
Identification Methods	affinity chromatography technology, luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 908 Hs			1 1215
+	Hs
		1303946 PSMD1_HUMAN (59-845): 0: 790: 17.31		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		880711 PSMD2_HUMAN (1-908): 0: 1290: 100.00		HDAC4_HUMAN (405-873): 1.97e-147: 474: 36.51
+	Hs
		1027827 PSMD2_HUMAN (1-908): 0: 1290: 100.00		HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48
+	Hs
		1303961 PSMD1_HUMAN (59-845): 0: 790: 17.31		HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48