HitPredict

Interactor 1: PSMD2 (Q13200)
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
Gene: PSMD2

Interactor 2: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.754

Property	Details
Experiments	35271311, 26186194, 28514442, 33961781, 34761751, 19615732, 16990800, 18922472, 19490896
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 908 Hs			1 329
+	Hs
		1027738 PSMD2_HUMAN (1-908): 0: 1290: 100.00		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Sp
		953218 RPN1_SCHPO (8-905): 0: 1025: 47.67		UBLH2_SCHPO (7-325): 1.13e-114: 335: 38.77
+	Hs
		1303969 PSMD1_HUMAN (59-845): 0: 790: 17.31		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Dm
		1359021 PSMD1_DROME (59-845): 0: 710: 17.07		Q9XZ61_DROME (1-328): 2.79e-148: 421: 59.76
+	Sp
		251853 RPN2_SCHPO (59-844): 0: 667: 16.61		UBLH2_SCHPO (7-325): 1.13e-114: 335: 38.77
+	Hs
		1267105 PSMD1_HUMAN (59-845): 0: 790: 17.31		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29