HitPredict

Interactor 1: PSG4 (Q00888)
Pregnancy-specific beta-1-glycoprotein 4 (PS-beta-G-4) (PSBG-4) (Pregnancy-specific glycoprotein 4) (Pregnancy-specific beta-1-glycoprotein 9) (PS-beta-G-9) (PSBG-9) (Pregnancy-specific glycoprotein 9)
Gene: PSG4

Interactor 2: PSG3 (Q16557)
Pregnancy-specific beta-1-glycoprotein 3 (PS-beta-G-3) (PSBG-3) (Pregnancy-specific glycoprotein 3) (Carcinoembryonic antigen SG5)
Gene: PSG3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ig_2~Ig_2, Ig_2~Ig_3, Ig_2~V-set, Ig_3~Ig_3, Ig_3~V-set, V-set~V-set
Common GO terms	GO:0005576 - extracellular region GO:0007565 - female pregnancy
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 419 Hs			1 428
+	Hs
		1158745 PSG8_HUMAN (1-419): 3.48e-108: 327: 89.02		PSG3_HUMAN (1-428): 1.59e-100: 307: 100.00
+	Hs
		543423 PSG1_HUMAN (1-419): 2.03e-105: 319: 88.54		PSG3_HUMAN (1-428): 1.59e-100: 307: 100.00
+	Hs
		543421 PSG1_HUMAN (1-419): 2.03e-105: 319: 88.54		PSG5_HUMAN (122-428): 4.73e-55: 187: 58.72
+	Hs
		1027931 PSG4_HUMAN (1-419): 4.52e-111: 334: 100.00		PSG11_HUMAN (122-427): 4.22e-49: 171: 42.03
+	Hs
		1027932 PSG4_HUMAN (1-419): 4.52e-111: 334: 100.00		PSG8_HUMAN (2-337): 2.3e-32: 128: 22.81
+	Hs
		820595 CEAM3_HUMAN (1-149): 5.21e-68: 218: 56.38		CEAM3_HUMAN (1-147): 2.56e-68: 219: 56.46
+	Hs
		543416 PSG4_HUMAN (1-419): 4.52e-111: 334: 100.00		PSG1_HUMAN (4-242): 2.44e-18: 88.4: 18.67
+	Hs
		543445 PSG8_HUMAN (1-419): 3.48e-108: 327: 89.02		PSG1_HUMAN (4-242): 2.44e-18: 88.4: 18.67
+	Hs
		1027934 PSG8_HUMAN (1-419): 3.48e-108: 327: 89.02		PSG6_HUMAN (4-254): 1.36e-17: 86.5: 17.32
+	Hs
		543415 PSG1_HUMAN (1-419): 2.03e-105: 319: 88.54		PSG9_HUMAN (4-240): 5.95e-18: 87.3: 19.58
+	Hs
		543417 PSG1_HUMAN (1-419): 2.03e-105: 319: 88.54		PSG6_HUMAN (4-254): 1.36e-17: 86.5: 17.32
+	Ce
		109599 SAX3_CAEEL (2-408): 2.44e-54: 196: 13.53		SAX3_CAEEL (3-418): 2.92e-55: 199: 12.17
+	Hs
		567235 CEAM6_HUMAN (122-418): 1.14e-45: 162: 39.75		CEAM1_HUMAN (123-425): 2.63e-44: 163: 38.63
+	Hs
		445630 CEAM6_HUMAN (122-418): 1.14e-45: 162: 39.75		CEAM5_HUMAN (136-428): 2.16e-39: 151: 37.38
+	Dm
		233625 O44924_DROME (3-355): 1.35e-48: 179: 13.81		O44924_DROME (2-185): 8.25e-16: 81.9: 11.89