HitPredict

Interactor 1: DNJC3 (Q13217)
DnaJ homolog subfamily C member 3 (Endoplasmic reticulum DNA J domain-containing protein 6) (ER-resident protein ERdj6) (ERdj6) (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)
Gene: DNAJC3

Interactor 2: PTPRO (Q16827)
Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2)
Gene: PTPRO

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28330616, 28675297
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 1216
+	Hs
		1087959 TTC13_HUMAN (34-337): 1.83e-49: 183: 21.36		PTPRO_HUMAN (1-1216): 0: 2236: 100.00
+	Hs
		1087989 DJB12_HUMAN (381-495): 7.69e-35: 136: 36.98		PTPRO_HUMAN (1-1216): 0: 2236: 100.00
+	Hs
		1087952 TMTC3_HUMAN (9-308): 2.55e-27: 118: 11.59		PTPRO_HUMAN (1-1216): 0: 2236: 100.00
+	Hs
		1087993 DJB11_HUMAN (393-474): 8.51e-14: 74.7: 51.81		PTPRO_HUMAN (1-1216): 0: 2236: 100.00
+	Hs
		1305077 DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05		PTN18_HUMAN (919-1216): 2.35e-120: 382: 30.52
+	Hs
		684983 STIP1_HUMAN (24-460): 7.31e-16: 82: 10.91		PTN18_HUMAN (919-1216): 2.35e-120: 382: 30.52
+	Hs
		1269184 DNJB9_HUMAN (391-503): 1.35e-35: 134: 35.77		PTPRU_HUMAN (918-1200): 4.38e-58: 222: 29.63
+	Hs
		1069984 DNJB9_HUMAN (391-503): 1.35e-35: 134: 35.77		PTPRK_HUMAN (917-1199): 1.9e-57: 220: 29.20
+	Hs
		1269185 DJB11_HUMAN (393-474): 8.51e-14: 74.7: 51.81		PTPRU_HUMAN (918-1200): 4.38e-58: 222: 29.63