Interactor 1: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2
Interactor 2: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 0.90 | 0.708 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20588255 |
| Identification Methods | pull down, enzymatic study, affinity chromatography technology |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Histone~zf-C3HC4_3, Histone~zf-RanBP |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
