HitPredict

Interactor 1: M3K1 (Q13233)
Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) (EC 2.3.2.27)
Gene: MAP3K1

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1512 Hs			1 451
+	Hs
		428180 M3K1_HUMAN (1-1512): 0: 1994: 100.00		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		408596 KPCB_HUMAN (899-1509): 2.67e-127: 413: 15.40		TBA4A_HUMAN (1-450): 0: 717: 96.00
+	Hs
		1081933 PKN1_HUMAN (777-1512): 3.49e-122: 407: 14.62		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Hs
		428232 PKN1_HUMAN (777-1512): 3.49e-122: 407: 14.62		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		397156 KPCG_HUMAN (899-1509): 4.13e-124: 405: 16.04		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Hs
		625584 CDK2_HUMAN (1243-1509): 1.1e-104: 337: 25.85		TBA1C_HUMAN (1-451): 0: 726: 98.00
+	Hs
		625344 CDK2_HUMAN (1243-1509): 1.1e-104: 337: 25.85		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Hs
		1175130 M3K3_HUMAN (1243-1505): 1.2e-51: 195: 44.03		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Hs
		428385 M3K3_HUMAN (1243-1505): 1.2e-51: 195: 44.03		TBB5_HUMAN (1-439): 0: 695: 40.77