HitPredict

Interactor 1: SRSF5 (Q13243)
Serine/arginine-rich splicing factor 5 (Delayed-early protein HRS) (Pre-mRNA-splicing factor SRP40) (Splicing factor, arginine/serine-rich 5)
Gene: SRSF5

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	29509190, 21182203, 25604459
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 272 Hs			1 530
+	Hs
		993786 SRSF4_HUMAN (5-265): 3.78e-51: 176: 53.64		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1028586 SRSF9_HUMAN (2-211): 1.47e-52: 172: 33.02		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369476 SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369528 SRSF5_HUMAN (1-240): 2.63e-54: 178: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369529 SRSF6_HUMAN (5-184): 1.35e-48: 165: 61.96		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1031409 PABP4_HUMAN (104-189): 3.45e-16: 80.1: 21.98		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1119140 PAP1L_HUMAN (105-189): 5.16e-16: 79.4: 16.67		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		377273 SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377296 SRSF5_HUMAN (1-240): 2.63e-54: 178: 100.00		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377295 SRSF9_HUMAN (2-211): 1.47e-52: 172: 33.02		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		370350 RBM4_HUMAN (3-122): 5.32e-17: 81.7: 22.50		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369534 PABP4_HUMAN (104-189): 3.45e-16: 80.1: 21.98		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369739 PAP1L_HUMAN (105-189): 5.16e-16: 79.4: 16.67		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		368886 PABP1_HUMAN (98-189): 1.16e-15: 78.6: 18.56		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		377649 RBM4_HUMAN (3-122): 5.32e-17: 81.7: 22.50		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		782537 PABP4_HUMAN (104-189): 3.45e-16: 80.1: 21.98		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		611434 PABP4_HUMAN (104-189): 3.45e-16: 80.1: 21.98		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30
+	Hs
		487369 SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487396 SRSF9_HUMAN (2-211): 1.47e-52: 172: 33.02		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487081 PABP1_HUMAN (98-189): 1.16e-15: 78.6: 18.56		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59