HitPredict

Interactor 1: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28977666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 344 Hs			1 1912
+	Hs
		992774 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1028548 SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1028656 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1031332 PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1059904 RBM28_HUMAN (4-248): 1.53e-12: 70.6: 14.61		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		516522 PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		951965 SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		992741 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018454 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018455 SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018458 PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018715 RBM28_HUMAN (4-248): 1.53e-12: 70.6: 14.61		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		516483 PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		951935 SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Dm
		332738 SRR55_DROME (3-337): 3.03e-47: 165: 46.86		CHDM_DROME (1-1904): 0: 1364: 50.85
+	Sc
		697423 NOP3_YEAST (3-326): 1.19e-19: 91.2: 19.94		CHD1_YEAST (515-1383): 0: 777: 35.17
+	Hs
		516702 PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		151398 SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84		CHD1_HUMAN (491-1733): 0: 734: 27.99