HitPredict

Interactor 1: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Interactor 2: RPF1 (Q9H9Y2)
Ribosome production factor 1 (Brix domain-containing protein 5) (Ribosome biogenesis protein RPF1)
Gene: RPF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 344 Hs			1 349
+	Hs
		992941 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		RPF1_HUMAN (1-349): 2e-138: 398: 100.00
+	Hs
		1028827 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		RPF1_HUMAN (1-349): 2e-138: 398: 100.00
+	Hs
		1308774 RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23		RPF1_HUMAN (1-349): 2e-138: 398: 100.00
+	Hs
		992881 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		IMP4_HUMAN (65-347): 1.31e-112: 330: 29.72
+	Hs
		993798 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		IMP4_HUMAN (65-347): 1.31e-112: 330: 29.72
+	Hs
		1028772 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		IMP4_HUMAN (65-347): 1.31e-112: 330: 29.72
+	Hs
		1291763 RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23		IMP4_HUMAN (65-347): 1.31e-112: 330: 29.72
+	Hs
		1029034 SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00		IMP4_HUMAN (65-347): 1.31e-112: 330: 29.72
+	Hs
		1255200 RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05		BRX1_HUMAN (84-346): 1.15e-86: 266: 20.96
+	Hs
		993779 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		BRX1_HUMAN (84-346): 1.15e-86: 266: 20.96
+	Hs
		1028748 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		BRX1_HUMAN (84-346): 1.15e-86: 266: 20.96
+	Hs
		1255192 RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23		BRX1_HUMAN (84-346): 1.15e-86: 266: 20.96
+	Hs
		1029012 SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00		BRX1_HUMAN (84-346): 1.15e-86: 266: 20.96
+	Hs
		952053 SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84		BRX1_HUMAN (84-346): 1.15e-86: 266: 20.96
+	Sc
		376951 PABP_YEAST (99-194): 1.33e-11: 67.6: 19.80		BRX1_YEAST (113-345): 1.97e-71: 225: 17.53