HitPredict

Interactor 1: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Interactor 2: TR150 (Q9Y2W1)
Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150)
Gene: THRAP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000381 - regulation of alternative mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 344 Hs			1 955
+	Hs
		993001 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Hs
		993875 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Hs
		952185 SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Hs
		1028627 SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		1029137 SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		1191715 RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		993755 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		1028977 SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		952014 SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		992995 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		993872 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		1028876 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		1029163 SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		965152 PABP3_HUMAN (101-191): 1.24e-10: 64.5: 19.79		ANK2_HUMAN (47-877): 6.14e-50: 195: 12.46
+	Hs
		992772 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Hs
		1028547 SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Hs
		516749 PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		952179 SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		1031405 PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20
+	Hs
		516609 PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20