HitPredict

Interactor 1: MD2L1 (Q13257)
Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1)
Gene: MAD2L1

Interactor 2: APC7 (Q9UJX3)
Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7)
Gene: ANAPC7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26986935, 33961781
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0051301 - cell division
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 565
+	Hs
		1029248 MD2L1_HUMAN (1-205): 1.58e-99: 288: 100.00		Q4KMX6_HUMAN (2-565): 1.18e-103: 325: 100.00
+	Sp
		145600 MAD2_SCHPO (3-201): 9.71e-83: 245: 45.50		CUT9_SCHPO (9-521): 1.18e-51: 189: 13.36
+	Hs
		1022894 MD2L1_HUMAN (1-205): 1.58e-99: 288: 100.00		CDC16_HUMAN (134-544): 8.61e-16: 82.5: 12.56
+	Hs
		1029345 MD2L1_HUMAN (1-205): 1.58e-99: 288: 100.00		CDC23_HUMAN (241-545): 1.19e-12: 72.5: 12.04
+	Hs
		672824 MD2L1_HUMAN (1-205): 1.58e-99: 288: 100.00		CDC27_HUMAN (20-196): 9.88e-12: 69.8: 10.70
+	Sp
		145598 MAD2_SCHPO (3-201): 9.71e-83: 245: 45.50		APC8_SCHPO (227-545): 5.78e-10: 64: 11.37
+	Sc
		454914 MAD2_YEAST (9-200): 6.6e-76: 228: 43.15		CDC16_YEAST (214-535): 5.91e-15: 80.2: 11.55
+	Hs
		672915 MD2L2_HUMAN (17-203): 6e-62: 193: 22.73		CDC27_HUMAN (20-196): 9.88e-12: 69.8: 10.70