Interactor 1: MD2L1 (Q13257)
Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1)
Gene: MAD2L1

Interactor 2: MD1L1 (Q9Y6D9)
Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181)
Gene: MAD1L1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.994

The method score is based on:

Property Details
Experiments 16189514, 26496610, 26986935, 11707408, 21041666, 25422469, 29997244, 26264872, 10660610, 33961781, 11804586, 11459826, 15694304, 21772247, 18318601, 32296183, 31588029, 21525009, 21988832, 24581499 and 8 others

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Identification Methods two hybrid, affinity chromatography technology, pull down, fluorescent resonance energy transfer, unspecified method, biochemical, molecular sieving, anti tag coimmunoprecipitation, nuclear magnetic resonance, anti bait coimmunoprecipitation and 8 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HORMA~MAD
Common GO terms GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 6 others

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Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 205
Hs

1 718
+ Dm
+ At
+ Hs
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024