HitPredict

Interactor 1: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Interactor 2: FHL3 (Q13643)
Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM-protein 2) (SLIM-2)
Gene: FHL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29955894
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 835 Hs			1 280
+	Hs
		816239 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		LIMS1_HUMAN (37-278): 1.46e-46: 160: 23.48
+	Hs
		1029412 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		FHL2_HUMAN (4-156): 1.41e-24: 101: 26.45
+	Hs
		668667 PML_HUMAN (29-609): 1.21e-57: 214: 14.00		FHL3_HUMAN (1-280): 8.02e-79: 241: 100.00
+	Hs
		668516 PML_HUMAN (29-609): 1.21e-57: 214: 14.00		PAXI_HUMAN (3-218): 4.3e-73: 236: 28.70
+	Hs
		1044739 TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32		FHL3_HUMAN (1-280): 8.02e-79: 241: 100.00
+	Mm
		1307943 TRIM8_MOUSE (59-590): 3.71e-48: 181: 15.52		FHL3_MOUSE (1-280): 1.6e-74: 230: 94.46
+	Hs
		175706 TRI18_HUMAN (56-644): 5.73e-67: 237: 13.78		PDLI5_HUMAN (3-155): 6.13e-48: 169: 28.76
+	Hs
		668514 PML_HUMAN (29-609): 1.21e-57: 214: 14.00		LIMS1_HUMAN (37-278): 1.46e-46: 160: 23.48
+	Hs
		1293392 TRI56_HUMAN (47-532): 1.21e-51: 195: 17.68		PDLI5_HUMAN (3-155): 6.13e-48: 169: 28.76
+	Hs
		668885 PML_HUMAN (29-609): 1.21e-57: 214: 14.00		LPP_HUMAN (3-153): 3.55e-38: 143: 29.38
+	Hs
		1190445 TRI63_HUMAN (53-406): 8.26e-61: 211: 15.56		LIMS2_HUMAN (100-278): 1.24e-31: 121: 23.91
+	Hs
		584958 RO52_HUMAN (104-502): 1.58e-48: 180: 12.94		FHL1_HUMAN (66-279): 2.38e-43: 151: 29.17
+	Hs
		150526 PML_HUMAN (29-609): 1.21e-57: 214: 14.00		ABLM1_HUMAN (3-147): 6.59e-28: 114: 24.03
+	Hs
		668677 PML_HUMAN (29-609): 1.21e-57: 214: 14.00		FHL2_HUMAN (4-156): 1.41e-24: 101: 26.45
+	Hs
		1050741 TRI63_HUMAN (53-406): 8.26e-61: 211: 15.56		FHL2_HUMAN (4-156): 1.41e-24: 101: 26.45
+	Dm
		112254 TRIM9_DROME (103-502): 2.92e-53: 200: 15.53		Q8INQ9_DROME (100-278): 6.01e-28: 111: 22.28
+	Dm
		112255 TRIM9_DROME (103-502): 2.92e-53: 200: 15.53		Q8INR0_DROME (100-278): 6.22e-28: 111: 22.28
+	Hs
		1190448 TRI55_HUMAN (41-610): 9.71e-50: 186: 14.21		LIMS2_HUMAN (100-278): 1.24e-31: 121: 23.91
+	Hs
		1050767 TRI55_HUMAN (41-610): 9.71e-50: 186: 14.21		FHL2_HUMAN (4-156): 1.41e-24: 101: 26.45
+	Ce
		107581 NCL1_CAEEL (123-467): 1.23e-35: 147: 18.23		G5EFG1_CAEEL (3-150): 2.87e-13: 71.6: 26.00