HitPredict

Interactor 1: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Interactor 2: ZN331 (Q9NQX6)
Zinc finger protein 331 (C2H2-like zinc finger protein rearranged in thyroid adenomas) (Zinc finger protein 361) (Zinc finger protein 463)
Gene: ZNF331

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 835 Hs			1 463
+	Hs
		563268 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN708_HUMAN (47-442): 0: 552: 47.73
+	Hs
		64159 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN726_HUMAN (3-462): 0: 551: 43.49
+	Hs
		977874 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF85_HUMAN (48-437): 0: 549: 49.23
+	Hs
		1029501 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		Z585B_HUMAN (48-462): 0: 540: 44.34
+	Hs
		728566 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF93_HUMAN (47-438): 0: 534: 45.66
+	Hs
		977953 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF92_HUMAN (46-462): 0: 522: 44.37
+	Hs
		264762 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN254_HUMAN (47-380): 8.58e-152: 448: 45.51
+	Hs
		1029423 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN235_HUMAN (2-462): 8.02e-139: 417: 33.77
+	Hs
		67425 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN850_HUMAN (122-461): 2.36e-116: 368: 58.24
+	Hs
		73013 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		B4DU56_HUMAN (48-324): 1.35e-115: 353: 42.60
+	Hs
		549159 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN250_HUMAN (62-265): 4.08e-77: 252: 40.20
+	Hs
		1029491 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN829_HUMAN (251-461): 8.19e-70: 229: 58.29
+	Hs
		563805 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF30_HUMAN (285-463): 2.45e-43: 163: 51.40
+	Hs
		846675 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF84_HUMAN (48-158): 6.79e-30: 125: 19.82
+	Hs
		1029422 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN268_HUMAN (47-158): 3.17e-29: 123: 21.43
+	Hs
		997541 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN543_HUMAN (48-168): 2.98e-28: 119: 22.31
+	Hs
		1029425 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN273_HUMAN (47-158): 1.91e-26: 113: 16.96
+	Hs
		67864 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN724_HUMAN (48-160): 1.64e-24: 108: 16.81
+	Hs
		258851 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		Z780A_HUMAN (120-185): 6.31e-14: 75.9: 59.09
+	Hs
		1029432 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN846_HUMAN (48-130): 4.68e-10: 63.4: 8.43