HitPredict

Interactor 1: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Interactor 2: IF2B1 (Q9NZI8)
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)
Gene: IGF2BP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29955894
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 835 Hs			1 577
+	Hs
		128163 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		1102503 LIN41_HUMAN (142-395): 1.53e-66: 240: 24.19		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		127941 TIF1A_HUMAN (404-808): 1.31e-52: 200: 21.55		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		170496 TIF1A_HUMAN (404-808): 1.31e-52: 200: 21.55		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		128021 RO52_HUMAN (104-502): 1.58e-48: 180: 12.94		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		1030079 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		1029737 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		1029450 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		668890 PML_HUMAN (29-609): 1.21e-57: 214: 14.00		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		1310873 TRI56_HUMAN (47-532): 1.21e-51: 195: 17.68		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		1283867 TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		668704 PML_HUMAN (29-609): 1.21e-57: 214: 14.00		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		1294236 TRI56_HUMAN (47-532): 1.21e-51: 195: 17.68		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		1273099 TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Hs
		1071988 TRI56_HUMAN (47-532): 1.21e-51: 195: 17.68		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17