HitPredict

Interactor 1: STX3 (Q13277)
Syntaxin-3
Gene: STX3

Interactor 2: STXB5 (Q5T5C0)
Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1)
Gene: STXBP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008021 - synaptic vesicle GO:0031201 - SNARE complex
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 289 Hs			1 1151
+	Hs
		699268 STX2_HUMAN (1-287): 3.91e-77: 238: 63.45		STXB5_HUMAN (1-1151): 0: 1143: 100.00
+	Hs
		1083937 STX1A_HUMAN (1-286): 4.49e-75: 233: 62.98		STXB5_HUMAN (1-1151): 0: 1143: 100.00
+	Hs
		1017663 STX4_HUMAN (1-286): 8.41e-62: 199: 39.32		STXB5_HUMAN (1-1151): 0: 1143: 100.00
+	Mm
		936826 STX4_MOUSE (1-286): 1.78e-60: 195: 40.00		STXB5_MOUSE (1-1151): 0: 1127: 96.88
+	Hs
		269433 STX11_HUMAN (1-273): 2.64e-52: 174: 29.37		STXB5_HUMAN (1-1151): 0: 1143: 100.00
+	Hs
		1133592 STX19_HUMAN (1-260): 5.88e-51: 171: 30.82		STXB5_HUMAN (1-1151): 0: 1143: 100.00
+	Hs
		1133591 STX12_HUMAN (28-270): 8.2e-51: 170: 25.91		STXB5_HUMAN (1-1151): 0: 1143: 100.00
+	Hs
		178582 STX7_HUMAN (37-284): 2.99e-48: 163: 25.79		STXB5_HUMAN (1-1151): 0: 1143: 100.00
+	Hs
		699292 STX2_HUMAN (1-287): 3.91e-77: 238: 63.45		STB5L_HUMAN (1-1151): 0: 1051: 63.82
+	Hs
		1233518 STX19_HUMAN (1-260): 5.88e-51: 171: 30.82		STB5L_HUMAN (1-1151): 0: 1051: 63.82
+	Hs
		1205402 STX12_HUMAN (28-270): 8.2e-51: 170: 25.91		STB5L_HUMAN (1-1151): 0: 1051: 63.82
+	Ce
		183454 STX1A_CAEEL (2-282): 5.06e-72: 225: 56.18		Q14DX2_CAEEL (14-1151): 0: 802: 34.99
+	Hs
		1030142 STX3_HUMAN (1-289): 6.42e-71: 222: 100.00		L2GL1_HUMAN (35-1142): 0: 697: 25.19
+	Hs
		1017639 STX4_HUMAN (1-286): 8.41e-62: 199: 39.32		L2GL1_HUMAN (35-1142): 0: 697: 25.19
+	Hs
		178544 STX7_HUMAN (37-284): 2.99e-48: 163: 25.79		L2GL1_HUMAN (35-1142): 0: 697: 25.19
+	Sc
		699533 SSO1_YEAST (28-267): 1.98e-47: 161: 24.59		SRO7_YEAST (11-676): 2.57e-68: 251: 15.95