HitPredict

Interactor 1: G3BP1 (Q13283)
Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)
Gene: G3BP1

Interactor 2: IF4H (Q15056)
Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein)
Gene: EIF4H

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26777405
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 466 Hs			1 248
+	Hs
		618614 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		IF4B_HUMAN (33-208): 3.57e-31: 122: 32.78
+	Hs
		963512 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		TIAR_HUMAN (36-248): 1.25e-31: 121: 11.63
+	Hs
		516494 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		PABP1_HUMAN (33-237): 3.05e-27: 111: 15.46
+	Hs
		1030211 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		PABP4_HUMAN (33-219): 4.09e-24: 102: 13.54
+	Mm
		957015 G3BP1_MOUSE (1-466): 7.3e-96: 298: 93.36		ELAV4_MOUSE (35-123): 2.56e-22: 95.9: 25.28
+	Hs
		680445 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		TIA1_HUMAN (10-219): 1.78e-15: 76.7: 12.26
+	Hs
		618736 G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68		IF4B_HUMAN (33-208): 3.57e-31: 122: 32.78
+	Hs
		516742 G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68		PABP1_HUMAN (33-237): 3.05e-27: 111: 15.46
+	Hs
		1031497 G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68		PABP4_HUMAN (33-219): 4.09e-24: 102: 13.54
+	Hs
		1054666 G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68		RBM39_HUMAN (21-248): 5.04e-22: 96.3: 13.10
+	Zm
		22429 A0A1D6Q2L8_MAIZE (6-437): 3.94e-61: 208: 23.45		A0A1D6I0G1_MAIZE (42-248): 4.55e-24: 102: 14.15
+	Hs
		1054335 SAFB1_HUMAN (93-439): 7.61e-35: 140: 12.39		RBM39_HUMAN (21-248): 5.04e-22: 96.3: 13.10
+	Sc
		648407 BRE5_YEAST (9-441): 5.6e-45: 166: 15.31		NSR1_YEAST (30-140): 9.72e-10: 60.2: 19.47
+	Hs
		963566 CELF4_HUMAN (297-422): 1.94e-13: 74.3: 15.91		TIAR_HUMAN (36-248): 1.25e-31: 121: 11.63
+	Hs
		963554 CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29		TIAR_HUMAN (36-248): 1.25e-31: 121: 11.63
+	Hs
		516621 CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29		PABP1_HUMAN (33-237): 3.05e-27: 111: 15.46
+	Dm
		597049 RB27C_DROME (319-464): 1.03e-12: 71.6: 22.15		PABP_DROME (43-213): 1.11e-23: 101: 15.03
+	Hs
		1031413 CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29		PABP4_HUMAN (33-219): 4.09e-24: 102: 13.54
+	Zm
		18728 A0A1D6H7I7_MAIZE (337-436): 2.76e-12: 69.6: 26.85		O48554_MAIZE (38-118): 1.15e-26: 102: 22.89
+	Hs
		1054482 CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29		RBM39_HUMAN (21-248): 5.04e-22: 96.3: 13.10