HitPredict

Interactor 1: G3BP1 (Q13283)
Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)
Gene: G3BP1

Interactor 2: Z3H7A (Q8IWR0)
Zinc finger CCCH domain-containing protein 7A
Gene: ZC3H7A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	26777405, 29395067, 30995489
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 466 Hs			1 971
+	Hs
		1030536 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		Z3H7B_HUMAN (7-969): 0: 1074: 44.56
+	Hs
		1219267 G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68		Z3H7A_HUMAN (1-971): 0: 1124: 100.00
+	Hs
		1219208 CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29		Z3H7A_HUMAN (1-971): 0: 1124: 100.00
+	Hs
		1030469 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		HELZ2_HUMAN (418-802): 2.14e-63: 237: 22.85
+	Hs
		684685 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		STIP1_HUMAN (40-400): 6.8e-30: 127: 10.41
+	Hs
		1030264 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		TOM34_HUMAN (42-197): 1.23e-12: 71.8: 24.85
+	Zm
		21263 A0A1D6IIC3_MAIZE (7-466): 7.23e-54: 188: 21.94		A0A1D6HSP5_MAIZE (1-441): 4.56e-53: 197: 16.74