HitPredict

Interactor 1: G3BP1 (Q13283)
Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)
Gene: G3BP1

Interactor 2: DHX40 (Q8IX18)
Probable ATP-dependent RNA helicase DHX40 (EC 3.6.4.13) (DEAH box protein 40) (Protein PAD)
Gene: DHX40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003724 - RNA helicase activity GO:0005524 - ATP binding GO:0016887 - ATP hydrolysis activity
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 466 Hs			1 779
+	Hs
		1030480 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		DHX36_HUMAN (6-776): 0: 737: 23.99
+	Hs
		1073525 SAFB1_HUMAN (93-439): 7.61e-35: 140: 12.39		DHX40_HUMAN (1-779): 0: 782: 100.00
+	Hs
		1055378 SAFB1_HUMAN (93-439): 7.61e-35: 140: 12.39		DHX8_HUMAN (45-733): 0: 731: 41.51
+	Hs
		994397 G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68		DHX9_HUMAN (5-773): 0: 622: 22.49
+	Sc
		859392 BRE5_YEAST (9-441): 5.6e-45: 166: 15.31		PRP43_YEAST (9-732): 0: 695: 36.33
+	Sc
		622328 BRE5_YEAST (9-441): 5.6e-45: 166: 15.31		PRP22_YEAST (5-746): 0: 688: 36.33
+	Hs
		1220247 CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29		DHX40_HUMAN (1-779): 0: 782: 100.00
+	Sc
		554237 BRE5_YEAST (9-441): 5.6e-45: 166: 15.31		PRP16_YEAST (6-749): 0: 644: 35.37