HitPredict

Interactor 1: G3BP1 (Q13283)
Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)
Gene: G3BP1

Interactor 2: RB12B (Q8IXT5)
RNA-binding protein 12B (RNA-binding motif protein 12B)
Gene: RBM12B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26777405
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 466 Hs			1 1001
+	Hs
		680445 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		TIA1_HUMAN (3-285): 2.5e-25: 111: 8.81
+	Hs
		963512 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		TIAR_HUMAN (3-286): 4.25e-21: 98.6: 10.64
+	Hs
		878649 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		HNRH2_HUMAN (5-162): 7.84e-13: 73.8: 25.63
+	Hs
		516494 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		PABP1_HUMAN (3-284): 4.43e-12: 72: 11.58
+	Hs
		1030211 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		PABP4_HUMAN (3-156): 4.21e-11: 68.9: 11.11
+	Hs
		516742 G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68		PABP1_HUMAN (3-284): 4.43e-12: 72: 11.58
+	Hs
		1018119 G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68		GRSF1_HUMAN (381-492): 5.51e-12: 71.2: 21.37
+	Hs
		1031497 G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68		PABP4_HUMAN (3-156): 4.21e-11: 68.9: 11.11
+	Zm
		22429 A0A1D6Q2L8_MAIZE (6-437): 3.94e-61: 208: 23.45		A0A1D6I0G1_MAIZE (266-494): 1.94e-23: 108: 15.52
+	Dm
		597049 RB27C_DROME (319-464): 1.03e-12: 71.6: 22.15		PABP_DROME (5-578): 5.5e-65: 233: 11.22
+	Sc
		376881 BRE5_YEAST (9-441): 5.6e-45: 166: 15.31		PABP_YEAST (273-484): 3.14e-25: 113: 16.28
+	Hs
		855159 CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29		HNRPF_HUMAN (274-503): 2.76e-38: 150: 20.25
+	Ce
		1093632 Q20084_CAEEL (201-422): 3.25e-17: 85.8: 9.69		SYM2_CAEEL (2-318): 8.67e-28: 122: 19.09
+	Hs
		963566 CELF4_HUMAN (297-422): 1.94e-13: 74.3: 15.91		TIAR_HUMAN (3-286): 4.25e-21: 98.6: 10.64
+	Hs
		963554 CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29		TIAR_HUMAN (3-286): 4.25e-21: 98.6: 10.64
+	Hs
		682919 CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29		HNRH1_HUMAN (5-154): 1.62e-13: 76.1: 26.97
+	Hs
		516621 CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29		PABP1_HUMAN (3-284): 4.43e-12: 72: 11.58
+	Hs
		1017976 CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29		GRSF1_HUMAN (381-492): 5.51e-12: 71.2: 21.37
+	Hs
		1031413 CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29		PABP4_HUMAN (3-156): 4.21e-11: 68.9: 11.11
+	Dm
		822836 RB27C_DROME (319-464): 1.03e-12: 71.6: 22.15		Q9VGH5_DROME (277-356): 4.86e-10: 65.3: 19.75