HitPredict

Interactor 1: GPR17 (Q13304)
Uracil nucleotide/cysteinyl leukotriene receptor (UDP/CysLT receptor) (G-protein coupled receptor 17) (P2Y-like receptor) (R12)
Gene: GPR17

Interactor 2: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 367 Hs			1 3056
+	Hs
		1031594 LPAR4_HUMAN (44-336): 1.91e-83: 259: 31.67		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		723037 OPRM_HUMAN (9-365): 4.73e-73: 234: 21.04		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		723296 APJ_HUMAN (32-364): 1.02e-69: 224: 27.79		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		895616 CXCR4_HUMAN (28-340): 6.8e-70: 224: 23.27		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		798422 LPAR6_HUMAN (48-336): 8.83e-47: 164: 32.22		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		126587 P2Y10_HUMAN (61-336): 5.39e-40: 146: 35.69		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		1030924 GPR17_HUMAN (1-367): 4.06e-90: 276: 100.00		ATR_HUMAN (1223-3056): 0: 1214: 20.34
+	Hs
		723038 OPRM_HUMAN (9-365): 4.73e-73: 234: 21.04		ATR_HUMAN (1223-3056): 0: 1214: 20.34
+	Hs
		787471 GPR17_HUMAN (1-367): 4.06e-90: 276: 100.00		MTOR_HUMAN (1846-3055): 0: 843: 16.65
+	Hs
		723279 APJ_HUMAN (32-364): 1.02e-69: 224: 27.79		MTOR_HUMAN (1846-3055): 0: 843: 16.65
+	Hs
		787434 CXCR4_HUMAN (28-340): 6.8e-70: 224: 23.27		MTOR_HUMAN (1846-3055): 0: 843: 16.65
+	Hs
		944220 GPR17_HUMAN (1-367): 4.06e-90: 276: 100.00		PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20
+	Hs
		944388 LPAR4_HUMAN (44-336): 1.91e-83: 259: 31.67		PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20
+	Hs
		429015 ADRB2_HUMAN (39-364): 4.53e-70: 226: 17.31		PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20
+	Hs
		666304 NK3R_HUMAN (2-367): 7.33e-69: 225: 18.33		PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20
+	Hs
		126582 P2Y10_HUMAN (61-336): 5.39e-40: 146: 35.69		PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20
+	Mm
		936867 CXCR4_MOUSE (26-346): 1.3e-84: 262: 25.08		PK3CG_MOUSE (2446-2965): 4.69e-87: 313: 16.04
+	Hs
		787363 CXCR4_HUMAN (28-340): 6.8e-70: 224: 23.27		PK3CB_HUMAN (2385-3011): 9.82e-99: 348: 13.76
+	Hs
		822537 CXCR4_HUMAN (28-340): 6.8e-70: 224: 23.27		PK3CG_HUMAN (2437-2965): 4.25e-88: 316: 16.14
+	Hs
		126573 P2Y10_HUMAN (61-336): 5.39e-40: 146: 35.69		PK3CB_HUMAN (2385-3011): 9.82e-99: 348: 13.76