HitPredict

Interactor 1: PTK7 (Q13308)
Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7)
Gene: PTK7

Interactor 2: CEA21 (Q3KPI0)
Carcinoembryonic antigen-related cell adhesion molecule 21
Gene: CEACAM21

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ig_3~I-set, I-set~V-set, Ig_3~Ig_3, Ig_3~V-set
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1070 Hs			1 293
+	Dr
		65451 VGFR4_DANRE (10-1068): 3.97e-175: 549: 19.26		A8DZ85_DANRE (1-244): 1.84e-34: 134: 19.92
+	Hs
		725306 TIE1_HUMAN (55-1069): 5.14e-153: 486: 17.66		PSG5_HUMAN (4-242): 7.76e-23: 98: 16.60
+	Mm
		1149039 CNTN4_MOUSE (2-706): 9.4e-91: 315: 15.38		CNTN4_MOUSE (17-265): 3.1e-30: 121: 19.38
+	Hs
		508034 FGFR1_HUMAN (2-231): 7.15e-34: 142: 12.41		CEA21_HUMAN (1-293): 4.87e-75: 233: 100.00
+	Hs
		68223 FGFR1_HUMAN (2-231): 7.15e-34: 142: 12.41		HECA2_HUMAN (25-292): 2.84e-49: 171: 20.62
+	Dm
		1097967 ROR1_DROME (790-1061): 1.61e-57: 213: 39.42		PTK7_DROME (84-286): 1.03e-17: 85.1: 21.33
+	Hs
		685235 PTK7_HUMAN (2-329): 4.66e-52: 201: 19.94		CEAM8_HUMAN (5-253): 2.17e-20: 91.4: 15.56
+	Hs
		385273 NTRK1_HUMAN (555-1061): 3.09e-57: 214: 30.31		PXDN_HUMAN (1-137): 3.81e-14: 74.5: 16.67
+	Hs
		729273 PTK7_HUMAN (2-329): 4.66e-52: 201: 19.94		VGFR3_HUMAN (38-238): 2.33e-16: 81.3: 16.75
+	Hs
		385252 NTRK1_HUMAN (555-1061): 3.09e-57: 214: 30.31		TITIN_HUMAN (62-258): 8.3e-09: 58.7: 13.89
+	Hs
		572581 VGFR1_HUMAN (225-713): 1.05e-34: 146: 16.99		VGFR1_HUMAN (17-239): 1.67e-12: 69.7: 14.58
+	Hs
		1336269 ROBO2_HUMAN (590-799): 3.13e-11: 70.1: 14.16		ROBO2_HUMAN (3-235): 3.56e-35: 136: 17.08
+	Hs
		234601 DSCAM_HUMAN (4-607): 9.94e-17: 88.2: 10.76		ROBO1_HUMAN (126-282): 8.31e-22: 97.6: 15.39
+	Mm
		729404 VGFR2_MOUSE (4-222): 2.84e-22: 105: 20.25		VGFR3_MOUSE (39-238): 5.09e-15: 77.4: 15.39
+	Hs
		608212 FGFR4_HUMAN (2-127): 8.1e-14: 78.2: 17.73		ROBO1_HUMAN (126-282): 8.31e-22: 97.6: 15.39
+	Mm
		1142035 MUSK_MOUSE (130-422): 3.41e-12: 72.8: 22.59		MUSK_MOUSE (141-292): 4.1e-22: 98: 15.58
+	Hs
		1336275 ROBO2_HUMAN (590-799): 3.13e-11: 70.1: 14.16		ROBO1_HUMAN (126-282): 8.31e-22: 97.6: 15.39
+	Mm
		936322 DSCAM_MOUSE (250-577): 4.8e-16: 85.9: 12.11		DCC_MOUSE (5-264): 2.01e-14: 75.6: 9.46
+	Dm
		1149666 PTK7_DROME (34-247): 8.49e-13: 75.1: 24.20		PTK7_DROME (84-286): 1.03e-17: 85.1: 21.33
+	Hs
		1264771 TITIN_HUMAN (2-145): 6.21e-13: 75.9: 16.22		TITIN_HUMAN (62-258): 8.3e-09: 58.7: 13.89