HitPredict

Interactor 1: SKP2 (Q13309)
S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2)
Gene: SKP2

Interactor 2: LRC58 (Q96CX6)
Leucine-rich repeat-containing protein 58
Gene: LRRC58

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 424 Hs			1 371
+	Hs
		1031278 SKP2_HUMAN (1-424): 3e-94: 291: 100.00		LRC40_HUMAN (70-249): 9.27e-10: 62: 28.73
+	Dm
		1181694 SCRIB_DROME (91-424): 5.74e-39: 151: 15.04		SCRIB_DROME (4-301): 2.22e-56: 200: 25.84
+	At
		1323503 IMK2_ARATH (136-381): 6.63e-37: 145: 16.13		TDR_ARATH (11-361): 3.49e-45: 168: 20.05
+	At
		1351999 Q9XGZ2_ARATH (103-424): 1.95e-36: 144: 13.35		IMK2_ARATH (1-291): 6.77e-38: 146: 18.73
+	At
		85353 ERL2_ARATH (101-421): 1.15e-42: 162: 16.86		ERL1_ARATH (1-261): 9.46e-32: 128: 21.50
+	At
		85375 IRK_ARATH (50-422): 8.2e-37: 145: 13.29		ERL1_ARATH (1-261): 9.46e-32: 128: 21.50
+	At
		84594 ERL2_ARATH (101-421): 1.15e-42: 162: 16.86		RGI3_ARATH (181-363): 1.47e-17: 86.6: 24.19
+	At
		1114685 ERL2_ARATH (101-421): 1.15e-42: 162: 16.86		ERECT_ARATH (1-187): 6.54e-16: 81.2: 14.29
+	At
		99012 ERL2_ARATH (101-421): 1.15e-42: 162: 16.86		RGI4_ARATH (161-363): 6.01e-15: 78.5: 23.67
+	At
		84495 IRK_ARATH (50-422): 8.2e-37: 145: 13.29		GSO1_ARATH (136-363): 9.34e-19: 90: 18.80
+	At
		84507 Q9XGZ2_ARATH (103-424): 1.95e-36: 144: 13.35		GSO1_ARATH (136-363): 9.34e-19: 90: 18.80
+	At
		1167612 ERL2_ARATH (101-421): 1.15e-42: 162: 16.86		ERL2_ARATH (17-248): 4.03e-12: 69.7: 34.32
+	At
		84509 BRL2_ARATH (130-424): 4.29e-34: 137: 16.56		GSO1_ARATH (136-363): 9.34e-19: 90: 18.80
+	At
		1114722 Q9XGZ2_ARATH (103-424): 1.95e-36: 144: 13.35		ERECT_ARATH (1-187): 6.54e-16: 81.2: 14.29
+	At
		85103 ERL2_ARATH (101-421): 1.15e-42: 162: 16.86		RGI2_ARATH (1-129): 1.51e-09: 61.9: 17.42
+	At
		1167636 ERL2_ARATH (101-421): 1.15e-42: 162: 16.86		MIK1_ARATH (62-225): 8.34e-09: 59.3: 36.84
+	At
		83829 Q9XGZ2_ARATH (103-424): 1.95e-36: 144: 13.35		Y1561_ARATH (9-163): 1.42e-13: 74.2: 19.11
+	At
		221811 Q9XGZ2_ARATH (103-424): 1.95e-36: 144: 13.35		BAME1_ARATH (2-114): 1.5e-10: 65: 20.00
+	At
		1341098 Q9XGZ2_ARATH (103-424): 1.95e-36: 144: 13.35		BAME2_ARATH (1-112): 2.69e-10: 63.8: 17.54
+	At
		1338065 BRL2_ARATH (130-424): 4.29e-34: 137: 16.56		RGI1_ARATH (1-115): 2.01e-09: 61.5: 16.10