HitPredict

Interactor 1: SKP2 (Q13309)
S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2)
Gene: SKP2

Interactor 2: LRC40 (Q9H9A6)
Leucine-rich repeat-containing protein 40
Gene: LRRC40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 424 Hs			1 602
+	Hs
		232860 SKP2_HUMAN (1-424): 3e-94: 291: 100.00		PHLP1_HUMAN (82-555): 7.84e-25: 112: 25.00
+	At
		1378334 BRL2_ARATH (130-424): 4.29e-34: 137: 16.56		BRL2_ARATH (46-601): 1.7e-66: 237: 18.23
+	At
		85103 ERL2_ARATH (101-421): 1.15e-42: 162: 16.86		RGI2_ARATH (1-234): 1.1e-35: 145: 24.69
+	At
		99012 ERL2_ARATH (101-421): 1.15e-42: 162: 16.86		RGI4_ARATH (1-236): 5.49e-33: 137: 21.63
+	At
		84594 ERL2_ARATH (101-421): 1.15e-42: 162: 16.86		RGI3_ARATH (1-256): 1.6e-32: 135: 22.26
+	At
		221539 Q9XGZ2_ARATH (103-424): 1.95e-36: 144: 13.35		Y2317_ARATH (4-264): 1.35e-36: 148: 19.85
+	At
		1167629 ERL2_ARATH (101-421): 1.15e-42: 162: 16.86		FLS2_ARATH (4-234): 4.26e-30: 128: 21.81
+	At
		221811 Q9XGZ2_ARATH (103-424): 1.95e-36: 144: 13.35		BAME1_ARATH (14-265): 2.92e-34: 141: 21.62
+	At
		1341098 Q9XGZ2_ARATH (103-424): 1.95e-36: 144: 13.35		BAME2_ARATH (6-264): 4.36e-33: 137: 21.43
+	At
		1352203 BRL2_ARATH (130-424): 4.29e-34: 137: 16.56		Y1723_ARATH (211-600): 4.93e-35: 143: 19.10
+	At
		1323503 IMK2_ARATH (136-381): 6.63e-37: 145: 16.13		TDR_ARATH (6-279): 9.97e-31: 130: 18.31
+	At
		1324073 IRK_ARATH (50-422): 8.2e-37: 145: 13.29		FLS2_ARATH (4-234): 4.26e-30: 128: 21.81
+	At
		85408 ERL2_ARATH (101-421): 1.15e-42: 162: 16.86		HSL2_ARATH (354-601): 6.29e-21: 99.7: 14.57
+	At
		1338953 BRL2_ARATH (130-424): 4.29e-34: 137: 16.56		Y1571_ARATH (336-601): 6.15e-28: 121: 17.34
+	Dm
		1181694 SCRIB_DROME (91-424): 5.74e-39: 151: 15.04		SCRIB_DROME (460-602): 4.77e-23: 106: 22.92
+	At
		84495 IRK_ARATH (50-422): 8.2e-37: 145: 13.29		GSO1_ARATH (401-601): 6.52e-22: 102: 21.36
+	At
		84507 Q9XGZ2_ARATH (103-424): 1.95e-36: 144: 13.35		GSO1_ARATH (401-601): 6.52e-22: 102: 21.36
+	At
		84509 BRL2_ARATH (130-424): 4.29e-34: 137: 16.56		GSO1_ARATH (401-601): 6.52e-22: 102: 21.36
+	At
		1338065 BRL2_ARATH (130-424): 4.29e-34: 137: 16.56		RGI1_ARATH (361-600): 6.74e-20: 96.6: 19.51
+	At
		249746 BRL2_ARATH (130-424): 4.29e-34: 137: 16.56		BAME3_ARATH (332-601): 1.66e-15: 82.3: 17.69