HitPredict

Interactor 1: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Interactor 2: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 282
+	Hs
		516495 PABP4_HUMAN (1-644): 0: 585: 100.00		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		516502 PABP1_HUMAN (1-644): 0: 542: 74.54		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Hs
		516339 PABP1_HUMAN (1-644): 0: 542: 74.54		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		516689 PABP1_HUMAN (1-644): 0: 542: 74.54		PABP3_HUMAN (1-267): 3.29e-34: 132: 13.77
+	Hs
		516451 PABP1_HUMAN (1-644): 0: 542: 74.54		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		516471 PABP1_HUMAN (1-644): 0: 542: 74.54		TIAR_HUMAN (113-209): 9.67e-20: 89.4: 20.62
+	Mm
		665745 PABP1_MOUSE (1-644): 0: 542: 74.69		TIA1_MOUSE (114-207): 2.24e-18: 86: 21.28
+	Hs
		474022 PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Hs
		474021 PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05		PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13
+	Sc
		376562 PABP_YEAST (2-290): 4.28e-66: 228: 30.07		PABP_YEAST (12-109): 4.14e-09: 59: 9.18
+	Hs
		1040382 PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Hs
		516355 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		1119141 PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33		PAP1L_HUMAN (1-272): 4.36e-38: 143: 14.59
+	Hs
		516635 PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		925098 PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Mm
		857303 TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12		TRA2B_MOUSE (1-279): 2.66e-34: 127: 52.30
+	Zm
		8143 A0A1D6ELH4_MAIZE (1-89): 1.11e-15: 82.6: 30.34		A0A1D6ELH4_MAIZE (85-260): 5.46e-20: 91.3: 20.11