HitPredict

Interactor 1: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 644 Hs			1 759
+	Hs
		1031319 PABP4_HUMAN (1-644): 0: 585: 100.00		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		516506 PABP1_HUMAN (1-644): 0: 542: 74.54		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		516507 PABP1_HUMAN (1-644): 0: 542: 74.54		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1031317 PABP4_HUMAN (1-644): 0: 585: 100.00		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		516505 PABP1_HUMAN (1-644): 0: 542: 74.54		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1031315 PABP4_HUMAN (1-644): 0: 585: 100.00		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		1031316 PABP4_HUMAN (1-644): 0: 585: 100.00		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Hs
		516503 PABP1_HUMAN (1-644): 0: 542: 74.54		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		516504 PABP1_HUMAN (1-644): 0: 542: 74.54		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Hs
		1031416 PABP4_HUMAN (1-644): 0: 585: 100.00		CUL5_HUMAN (59-759): 0: 589: 24.94
+	Hs
		516626 PABP1_HUMAN (1-644): 0: 542: 74.54		CUL5_HUMAN (59-759): 0: 589: 24.94
+	Hs
		582279 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		582280 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		582278 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Mm
		449441 NUCL_MOUSE (3-89): 2.31e-20: 97.6: 31.03		CUL3_MOUSE (32-759): 0: 813: 38.36
+	Hs
		582276 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		680446 TIA1_HUMAN (4-109): 7.62e-12: 69.5: 24.53		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		582277 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Hs
		680447 TIA1_HUMAN (4-109): 7.62e-12: 69.5: 24.53		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Hs
		582420 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		CUL5_HUMAN (59-759): 0: 589: 24.94